CD26 (DPP IV / ADA-Binding Protein) Antibody - With BSA and Azide, Clone: [202.36], Mouse, Monoclonal
Artikelnummer:
ABT-AH11153-U0020
- Bilder (0)
| Artikelname: | CD26 (DPP IV / ADA-Binding Protein) Antibody - With BSA and Azide, Clone: [202.36], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH11153-U0020 |
| Hersteller Artikelnummer: | AH11153-U0020 |
| Alternativnummer: | ABT-AH11153-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, IHC-Fr |
| Spezies Reaktivität: | Human, Rat |
| Alternative Synonym: | Dipeptidyl peptidase 4, 3.4.14.5, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form, DPP4, ADCP2, CD26 |
| Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26. |
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