CD11a / Integrin alphaL / LFA-1 alpha Chain Antibody - With BSA and Azide, Clone: [DF1524], Mouse, Monoclonal
Artikelnummer:
ABT-AH11605-U0100
Hersteller Artikelnummer:
AH11605-U0100
Alternativnummer:
ABT-AH11605-U0100-100UG
Hersteller:
Abcepta
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FC, IF
Spezies Reaktivität:
Human
Alternative Synonym:
Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a, ITGAL, CD11A
Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV, Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.