CD10 (Membrane Metalloendopeptidase) Antibody - With BSA and Azide, Clone: [FR4D11], Mouse, Monoclonal
Artikelnummer:
ABT-AH11842-U0100
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| Artikelname: | CD10 (Membrane Metalloendopeptidase) Antibody - With BSA and Azide, Clone: [FR4D11], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH11842-U0100 |
| Hersteller Artikelnummer: | AH11842-U0100 |
| Alternativnummer: | ABT-AH11842-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN |
| Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkittā€(TM)s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. |
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