MUC1 / EMA / CD227 (Epithelial Marker) Antibody - With BSA and Azide, Clone: [VU-2G7], Mouse, Monoclonal
Artikelnummer:
ABT-AH11854-U0100
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| Artikelname: | MUC1 / EMA / CD227 (Epithelial Marker) Antibody - With BSA and Azide, Clone: [VU-2G7], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH11854-U0100 |
| Hersteller Artikelnummer: | AH11854-U0100 |
| Alternativnummer: | ABT-AH11854-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, IHC-P |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227, Mucin-1 subunit alpha, MUC1-NT, MUC1-alpha, Mucin-1 subunit beta, MUC1-beta, MUC1-CT, MUC1, PUM |
| MAb VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with epitope fingerprinting. The?extra cellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. |
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