CD31 / PECAM-1 (Endothelial Cell Marker) Antibody - With BSA and Azide, Clone: [158-2B3], Mouse, Monoclonal

Artikelnummer: ABT-AH12072-U0020
Artikelname: CD31 / PECAM-1 (Endothelial Cell Marker) Antibody - With BSA and Azide, Clone: [158-2B3], Mouse, Monoclonal
Artikelnummer: ABT-AH12072-U0020
Hersteller Artikelnummer: AH12072-U0020
Alternativnummer: ABT-AH12072-U0020-20UG
Hersteller: Abcepta
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF
Spezies Reaktivität: Human
Alternative Synonym: Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA, PECA1, CD31, PECAM1
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Klonalität: Monoclonal
Klon-Bezeichnung: [158-2B3]
NCBI: 5175
UniProt: P16284
Antibody Type: Monoclonal Antibody