CD71 / Transferrin Receptor (TFRC) Antibody - With BSA and Azide, Clone: [TFRC/1149], Mouse, Monoclonal
Artikelnummer:
ABT-AH12387-U0020
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| Artikelname: | CD71 / Transferrin Receptor (TFRC) Antibody - With BSA and Azide, Clone: [TFRC/1149], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH12387-U0020 |
| Hersteller Artikelnummer: | AH12387-U0020 |
| Alternativnummer: | ABT-AH12387-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD71, Transferrin receptor protein 1, serum form, sTfR, TFRC |
| It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. |
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