CD3e (T-Cell Marker) Antibody - With BSA and Azide, Clone: [CRIS-7], Mouse, Monoclonal
Artikelnummer:
ABT-AH12595-U0020
- Bilder (0)
| Artikelname: | CD3e (T-Cell Marker) Antibody - With BSA and Azide, Clone: [CRIS-7], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH12595-U0020 |
| Hersteller Artikelnummer: | AH12595-U0020 |
| Alternativnummer: | ABT-AH12595-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E |
| Recognizes the -chain of CD3 (Workshop V, Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. |
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