CD36 (Platelet & Microvessel Marker) Antibody - With BSA and Azide, Clone: [1E8.], Mouse, Monoclonal
Artikelnummer:
ABT-AH12726-U0020
- Bilder (0)
| Artikelname: | CD36 (Platelet & Microvessel Marker) Antibody - With BSA and Azide, Clone: [1E8.], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH12726-U0020 |
| Hersteller Artikelnummer: | AH12726-U0020 |
| Alternativnummer: | ABT-AH12726-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Platelet glycoprotein 4, Fatty acid translocase, FAT, Glycoprotein IIIb, GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein IV, GPIV, Thrombospondin receptor, CD36, CD36, GP3B, GP4 |
| Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. |
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