Anti-P-Cadherin (CDH3) Antibody, Clone: [6A9], Mouse, Monoclonal
Artikelnummer:
ABT-AH13077-U0100
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| Artikelname: | Anti-P-Cadherin (CDH3) Antibody, Clone: [6A9], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH13077-U0100 |
| Hersteller Artikelnummer: | AH13077-U0100 |
| Alternativnummer: | ABT-AH13077-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin |
| Recognizes a protein of 116kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy. |
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