Anti-Catenin, beta (p120) Antibody, Clone: [9F2], Mouse, Monoclonal
Artikelnummer:
ABT-AH13151-U0020
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| Artikelname: | Anti-Catenin, beta (p120) Antibody, Clone: [9F2], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH13151-U0020 |
| Hersteller Artikelnummer: | AH13151-U0020 |
| Alternativnummer: | ABT-AH13151-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Cadherin associated protein, beta 1 88kDa, Catenin beta-1, CATNB, CHBCAT, CTNNB1 |
| This MAb recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC. |
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