Anti-Connexin 32 (Gap Junction Protein) Antibody, Clone: [M12.13], Mouse, Monoclonal
Artikelnummer:
ABT-AH13265-U0100
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| Artikelname: | Anti-Connexin 32 (Gap Junction Protein) Antibody, Clone: [M12.13], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH13265-U0100 |
| Hersteller Artikelnummer: | AH13265-U0100 |
| Alternativnummer: | ABT-AH13265-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, IHC-Fr, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1 |
| This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. |
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