ABC29, ABCC1, ATP binding cassette sub family C (CFTR/MRP) member 1, ATP-binding cassette sub-family C member 1, GSX, Leukotriene C(4) transporter, LTC4 transporter, Multidrug resistance-associated protein 1 (MRP1)
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.