SKP2 Antibody - C-terminal region
Artikelnummer:
ASB-ARP30219_P050
- Bilder (3)
| Artikelname: | SKP2 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP30219_P050 |
| Hersteller Artikelnummer: | ARP30219_P050 |
| Alternativnummer: | ASB-ARP30219_P050-25UL,ASB-ARP30219_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of Human SKP2 |
| Alternative Synonym: | p45, FBL1, FLB1, FBXL1 |
| This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. |
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Host: Rabbit Target Name: SKP2 Sample Type: Colorectal Tumor lysates Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: SKP2 Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml |
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SKP2 Antibody - C-terminal region (ARP30219_P050) in Human Colorectal Tumor using Western Blot |
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