NFIL3 Antibody - middle region

Artikelnummer: ASB-ARP31177_P050
Artikelname: NFIL3 Antibody - middle region
Artikelnummer: ASB-ARP31177_P050
Hersteller Artikelnummer: ARP31177_P050
Alternativnummer: ASB-ARP31177_P050-25UL,ASB-ARP31177_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
Alternative Synonym: E4BP4, IL3BP1, NFIL3A, NF-IL3A
NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 51kDa
NCBI: 4783
UniProt: Q16649
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-NFIL3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human brain
Host: Mouse
Target Name: NFIL3
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml
NFIL3 antibody - middle region (ARP31177_P050) in Human Brain using Western Blot