VDR Antibody - N-terminal region
Artikelnummer:
ASB-ARP31243_P050
- Bilder (3)
| Artikelname: | VDR Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP31243_P050 |
| Hersteller Artikelnummer: | ARP31243_P050 |
| Alternativnummer: | ASB-ARP31243_P050-25UL,ASB-ARP31243_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human VDR |
| Alternative Synonym: | NR1I1, PPP1R163 |
| The nuclear hormone receptor for vitamin D3 also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. |
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WB Suggested Anti-VDR Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole CellThere is BioGPS gene expression data showing that VDR is expressed in Jurkat |
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Host: Mouse Target Name: VDR Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml |
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VDR antibody - N-terminal region (ARP31243_P050) in Human Jurkat using Western Blot |
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