COPS5 Antibody - N-terminal region
Artikelnummer:
ASB-ARP31512_P050
- Bilder (3)
| Artikelname: | COPS5 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP31512_P050 |
| Hersteller Artikelnummer: | ARP31512_P050 |
| Alternativnummer: | ASB-ARP31512_P050-25UL,ASB-ARP31512_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5 |
| Alternative Synonym: | CSN5, JAB1, SGN5, MOV-34 |
| COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-COPS5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: Human Muscle |
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Sample Type: ,1. ,Human blood cells, pure 2. ,Human blood cells, partially purified 3. and 4. Human total cell extract, extraction only Primary Dilution: ,1:500 Secondary Anitbody: ,HRP conjugated anti-rabbit Image Submitted By: ,Dr. Elah Pick University of Haifa at Oranim , |
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COPS5 antibody - N-terminal region (ARP31512_P050) in Human Muscle using Western Blot |
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