MTF1 Antibody - C-terminal region
Artikelnummer:
ASB-ARP32027_T100
- Bilder (3)
| Artikelname: | MTF1 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP32027_T100 |
| Hersteller Artikelnummer: | ARP32027_T100 |
| Alternativnummer: | ASB-ARP32027_T100-25UL,ASB-ARP32027_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1 |
| Alternative Synonym: | ZRF, MTF-1 |
| The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein. |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. |
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WB Suggested Anti-MTF1 Antibody Titration: 5.0ug/ml ELISA Titer: 1:2500 Positive Control: HepG2 cell lysateMTF1 is supported by BioGPS gene expression data to be expressed in HepG2 |
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MTF1 antibody - C-terminal region (ARP32027_T100) in Human HepG2 using Western Blot |
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