HNF1B Antibody - N-terminal region

Artikelnummer: ASB-ARP32320_P050
Artikelname: HNF1B Antibody - N-terminal region
Artikelnummer: ASB-ARP32320_P050
Hersteller Artikelnummer: ARP32320_P050
Alternativnummer: ASB-ARP32320_P050-25UL,ASB-ARP32320_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B
Alternative Synonym: T2D, FJHN, HNF2, LFB3, RCAD, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, ADTKD3, HNF-1B, HNF1beta, HNF-1-beta
Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 45kDa
NCBI: 6928
UniProt: P35680
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-HNF1B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Host: Rat
Target Name: HNF1B
Sample Tissue: Rat Liver
Antibody Dilution: 1ug/ml
HNF1B antibody - N-terminal region (ARP32320_P050) in Human Jurkat using Western Blot