PITX2 Antibody - N-terminal region
Artikelnummer:
ASB-ARP32432_P050
- Bilder (3)
| Artikelname: | PITX2 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP32432_P050 |
| Hersteller Artikelnummer: | ARP32432_P050 |
| Alternativnummer: | ASB-ARP32432_P050-25UL,ASB-ARP32432_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Equine, Human, Mouse |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PITX2 |
| Alternative Synonym: | RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, ASGD4, IGDS2, IRID2, Otlx2, RIEG1 |
| The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
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WB Suggested Anti-PITX2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:31250 Positive Control: Human heart |
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Host: Mouse Target Name: PITX2 Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml |
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PITX2 antibody - N-terminal region (ARP32432_P050) in Human Heart using Western Blot |
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