Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human APEX1
Alternative Synonym:
APE, APX, APE1, APEN, APEX, HAP1, REF1
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Lung
WB Suggested Anti-APEX1 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysateAPEX1 is supported by BioGPS gene expression data to be expressed in HepG2
APEX1 antibody - N-terminal region (ARP32651_T100) in Human HepG2 using Western Blot
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