Snf8 Antibody - N-terminal region
Artikelnummer:
ASB-ARP32857_P050
- Bilder (3)
| Artikelname: | Snf8 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP32857_P050 |
| Hersteller Artikelnummer: | ARP32857_P050 |
| Alternativnummer: | ASB-ARP32857_P050-25UL,ASB-ARP32857_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Alternative Synonym: | D11moh34, RGD1310144 |
| Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. |
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Rabbit Anti-Snf8 Antibody Catalog Number: ARP32857_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult liver Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 a€'' 2.0 sec Protocol located in Reviews and Data. |
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WB Suggested Anti-Snf8 Antibody Titration: 1.0 ug/ml Positive Control: Rat Liver |
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Snf8 antibody - N-terminal region (ARP32857_P050) in Rat Liver using Western Blot |
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