PSMC3 Antibody - middle region
Artikelnummer:
ASB-ARP32929_T100
- Bilder (3)
| Artikelname: | PSMC3 Antibody - middle region |
| Artikelnummer: | ASB-ARP32929_T100 |
| Hersteller Artikelnummer: | ARP32929_T100 |
| Alternativnummer: | ASB-ARP32929_T100-25UL,ASB-ARP32929_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human PSMC3 |
| Alternative Synonym: | RPT5, TBP1 |
| PSMC3 is a subunit of the 26S proteasome. 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9 |
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Human kidney |
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WB Suggested Anti-PSMC3 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate |
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PSMC3 antibody - middle region (ARP32929_T100) in Human HepG2 using Western Blot |
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