PLCG1 Antibody - C-terminal region

Artikelnummer: ASB-ARP33086_P050
Artikelname: PLCG1 Antibody - C-terminal region
Artikelnummer: ASB-ARP33086_P050
Hersteller Artikelnummer: ARP33086_P050
Alternativnummer: ASB-ARP33086_P050-25UL,ASB-ARP33086_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLCG1
Alternative Synonym: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 141 kDa
NCBI: 5335
UniProt: P19174
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PLCG1 Antibody
Catalog Number: ARP33086_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Plasma membrane, Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Host: Rabbit
Target Name: PLCG1
Sample Type: PANC1 Whole Cell
Antibody Dilution: 1.0ug/ml
PLCG1 Antibody - C-terminal region (ARP33086_P050) in PANC1 Whole Cell using Western Blot