ING3 Antibody - N-terminal region
Artikelnummer:
ASB-ARP33346_P050
- Bilder (3)
| Artikelname: | ING3 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP33346_P050 |
| Hersteller Artikelnummer: | ARP33346_P050 |
| Alternativnummer: | ASB-ARP33346_P050-25UL,ASB-ARP33346_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ING3 |
| Alternative Synonym: | Eaf4, ING2, MEAF4, p47ING3 |
| ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. |
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Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-ING3 antibody (ARP33346_P050) |
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WB Suggested Anti-ING3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate |
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ING3 antibody - N-terminal region (ARP33346_P050) in Human HepG2 using Western Blot |
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