ACTL6A Antibody - N-terminal region

Artikelnummer: ASB-ARP33350_P050
Artikelname: ACTL6A Antibody - N-terminal region
Artikelnummer: ASB-ARP33350_P050
Hersteller Artikelnummer: ARP33350_P050
Alternativnummer: ASB-ARP33350_P050-25UL,ASB-ARP33350_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTL6A
Alternative Synonym: Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 47kDa
NCBI: 86
UniProt: O96019
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ACTL6A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
Lanes:
1. Mouse WT brain extract (80ug) 2. Rat brain extract (80ug)
Primary Antibody Dilution:
2ug/ml
Secondary Antibody:
IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution:
1: 20,000
Gene Name:
ACTL6A
Submitted by:
Dr. Yuzhi Chen, University of Arkansas for Medical Science
ACTL6A antibody - N-terminal region (ARP33350_P050) in Transfected 293T using Western Blot