COPS2 Antibody - N-terminal region

Artikelnummer: ASB-ARP34189_P050
Artikelname: COPS2 Antibody - N-terminal region
Artikelnummer: ASB-ARP34189_P050
Hersteller Artikelnummer: ARP34189_P050
Alternativnummer: ASB-ARP34189_P050-25UL,ASB-ARP34189_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
Alternative Synonym: CSN2, SGN2, ALIEN, TRIP15
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 51kDa
NCBI: 9318
UniProt: P61201
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-COPS2 Antibody
Catalog Number: ARP34189_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes and endothelial cells in sinusoids
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-COPS2 Antibody
Titration: 0.5 ug/ml
Positive Control: Fetal Liver
COPS2 antibody - N-terminal region (ARP34189_P050) in Human Fetal liver using Western Blot