COPS2 Antibody - N-terminal region

Artikelnummer: ASB-ARP34189_T100
Artikelname: COPS2 Antibody - N-terminal region
Artikelnummer: ASB-ARP34189_T100
Hersteller Artikelnummer: ARP34189_T100
Alternativnummer: ASB-ARP34189_T100-25UL,ASB-ARP34189_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
Alternative Synonym: CSN2, SGN2, ALIEN, TRIP15
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/Ion ChannelSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 52kDa
NCBI: 9318
UniProt: P61201
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-COPS2 Antibody Titration: 0.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Sample Type: 1. Markers
2. B8 mouse fibroblast cells, extraction only
3. Human total cell extract
4. Human blood cells, partially purified
5. Pombe, extraction only
Primary Dilution: 1:200
Secondary Anitbody: HRP conjugated anti-rabbit
Image Submitted By: Dr. Elah Pick
University of Haifa at OranimA
COPS2 antibody - N-terminal region (ARP34189_T100) in Human Jurkat using Western Blot