Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human KLHL3
Alternative Synonym:
PHA2D
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Human brain stem cellsPrimary Antibody Dilution: 1:500Secondary Antibody: Goat anti-rabbit Alexa-Fluor 594Secondary Antibody Dilution: 1:1000Color/Signal Descriptions: KLHL3: Red DAPI:BlueGene Name: KLHL3Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science