TAF6 Antibody - N-terminal region
Artikelnummer:
ASB-ARP34693_T100
- Bilder (3)
| Artikelname: | TAF6 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP34693_T100 |
| Hersteller Artikelnummer: | ARP34693_T100 |
| Alternativnummer: | ASB-ARP34693_T100-25UL,ASB-ARP34693_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human TAF6 |
| Alternative Synonym: | ALYUS, TAF2E, TAFII70, TAFII80, TAFII85, MGC:8964, TAFII-70, TAFII-80, TAF(II)70, TAF(II)80 |
| TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis. |
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Human kidney |
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WB Suggested Anti-TAF6 Antibody Titration: 1.25ug/ml Positive Control: Transfected 293T |
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TAF6 antibody - N-terminal region (ARP34693_T100) in Transfected 293T using Western Blot |
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