SCN5A Antibody - C-terminal region

Artikelnummer: ASB-ARP34935_P050
Artikelname: SCN5A Antibody - C-terminal region
Artikelnummer: ASB-ARP34935_P050
Hersteller Artikelnummer: ARP34935_P050
Alternativnummer: ASB-ARP34935_P050-25UL,ASB-ARP34935_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCN5A
Alternative Synonym: HB1, HB2, HH1, IVF, VF1, HBBD, ICCD, LQT3, SSS1, CDCD2, CMD1E, CMPD2, PFHB1, Nav1.5
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 227kDa
NCBI: 6331
UniProt: Q14524
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-SCN5A Antibody
Catalog Number: ARP34935_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult heart
Observed Staining: Membrane (stronger than with ARP34934)
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Protocol located in Reviews and Data.
WB Suggested Anti-SCN5A Antibody Titration: HEK cel lysate, HEK cel with HuNav1.5 transfected lysate, Mouse Heart lysate80 ug protein on gelQC Antibodies 1:100 in PBS/Tweensecondary antibodie 1:10.000 ( IRDYE 800 CWGoat anti Rabbit IgG) analyse with the Licor Odyssey
Positive Control: HEK cel lysate, HEK cel with HuNav1.5 transfected lysate, Mouse Heart lysate80 ug protein on gelQC Antibodies 1:100 in PBS/Tweensecondary antibodie 1:10.000 ( IRDYE 800 CWGoat anti Rabbit IgG) analyse with the Licor Odyssey
SCN5A Antibody - C-terminal region (ARP34935_P050) in Human HEK using Western Blot