CHRNB2 Antibody - middle region
Artikelnummer:
ASB-ARP34970_T100
- Bilder (3)
| Artikelname: | CHRNB2 Antibody - middle region |
| Artikelnummer: | ASB-ARP34970_T100 |
| Hersteller Artikelnummer: | ARP34970_T100 |
| Alternativnummer: | ASB-ARP34970_T100-25UL,ASB-ARP34970_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2 |
| Alternative Synonym: | EFNL3, nAChRB2 |
| Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptors sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information. |
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Human kidney |
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WB Suggested Anti-CHRNB2 Antibody Titration: 2.5ug/ml Positive Control: Jurkat cell lysateCHRNB2 is supported by BioGPS gene expression data to be expressed in Jurkat |
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CHRNB2 antibody - middle region (ARP34970_T100) in Human Jurkat using Western Blot |
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