MCM6 Antibody - C-terminal region

Artikelnummer: ASB-ARP36650_T100
Artikelname: MCM6 Antibody - C-terminal region
Artikelnummer: ASB-ARP36650_T100
Hersteller Artikelnummer: ARP36650_T100
Alternativnummer: ASB-ARP36650_T100-25UL,ASB-ARP36650_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MCM6
Alternative Synonym: Mis5, P105MCM, MCG40308
The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 90kDa
NCBI: 4175
UniProt: Q14566
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Lung
WB Suggested Anti-MCM6 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
MCM6 antibody - C-terminal region (ARP36650_T100) in Human HepG2 using Western Blot