MCM7 Antibody - middle region
Artikelnummer:
ASB-ARP36652_T100
- Bilder (3)
| Artikelname: | MCM7 Antibody - middle region |
| Artikelnummer: | ASB-ARP36652_T100 |
| Hersteller Artikelnummer: | ARP36652_T100 |
| Alternativnummer: | ASB-ARP36652_T100-25UL,ASB-ARP36652_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Equine, Guinea pig, Human, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human MCM7 |
| Alternative Synonym: | MCM2, CDC47, P85MCM, P1CDC47, PNAS146, PPP1R104, P1.1-MCM3 |
| MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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Human kidney |
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WB Suggested Anti-MCM7 Antibody Titration: 1.25ug/ml Positive Control: Daudi cell lysateMCM7 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells |
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MCM7 antibody - middle region (ARP36652_T100) in Human Daudi using Western Blot |
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