MCM8 Antibody - N-terminal region

Artikelnummer: ASB-ARP36658_P050
Artikelname: MCM8 Antibody - N-terminal region
Artikelnummer: ASB-ARP36658_P050
Hersteller Artikelnummer: ARP36658_P050
Alternativnummer: ASB-ARP36658_P050-25UL,ASB-ARP36658_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MCM8
Alternative Synonym: POF10, C20orf154, dJ967N21.5
This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 94kDa
NCBI: 84515
UniProt: Q9UJA3
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-MCM8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
MCM8 WB Sample: siRNA Mock and siRNA MCM8 Dilution 1:1000
MCM8 antibody - N-terminal region (ARP36658_P050) in Human HepG2 using Western Blot