MCM8 Antibody - C-terminal region
Artikelnummer:
ASB-ARP36668_P050
- Bilder (3)
| Artikelname: | MCM8 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP36668_P050 |
| Hersteller Artikelnummer: | ARP36668_P050 |
| Alternativnummer: | ASB-ARP36668_P050-25UL,ASB-ARP36668_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human MCM8 |
| Alternative Synonym: | POF10, C20orf154, dJ967N21.5 |
| MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
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Human Intestine |
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WB Suggested Anti-MCM8 Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B cell lysate |
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MCM8 antibody - C-terminal region (ARP36668_P050) in Human 721_B using Western Blot |
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