Elf3 Antibody - N-terminal region

Artikelnummer: ASB-ARP36846_P050
Artikelname: Elf3 Antibody - N-terminal region
Artikelnummer: ASB-ARP36846_P050
Hersteller Artikelnummer: ARP36846_P050
Alternativnummer: ASB-ARP36846_P050-25UL,ASB-ARP36846_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Elf3
Alternative Synonym: ES, je, ESX, jen, ESE-, ESE-1
Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 41kDa
NCBI: 13710
UniProt: Q3UPW2-2
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Mouse Stomach
WB Suggested Anti-Elf3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Trachea
Elf3 antibody - N-terminal region (ARP36846_P050) in Human Trachea using Western Blot