THRB Antibody - N-terminal region
Artikelnummer:
ASB-ARP37994_P050
- Bilder (3)
| Artikelname: | THRB Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP37994_P050 |
| Hersteller Artikelnummer: | ARP37994_P050 |
| Alternativnummer: | ASB-ARP37994_P050-25UL,ASB-ARP37994_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ChIP, WB |
| Spezies Reaktivität: | Canine, Equine, Human, Mouse, Rabbit, Rat, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human THRB |
| Alternative Synonym: | GRTH, PRTH, THR1, ERBA2, NR1A2, THRB1, THRB2, C-ERBA-2, C-ERBA-BETA |
| THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length nature of only one has been determined so far. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. |
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Application: ,ChIP Sample type: mouse liver tissue Chromatin Used: 100ug tissue Antibody Used: 10ug , Image Submitted by: Joanna DiSpirito, , University of Pennsylvania , |
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WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human brain |
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THRB antibody - N-terminal region (ARP37994_P050) in Human brain using Western Blot |
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