JUNB Antibody - N-terminal region
Artikelnummer:
ASB-ARP38135_T100
- Bilder (3)
| Artikelname: | JUNB Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP38135_T100 |
| Hersteller Artikelnummer: | ARP38135_T100 |
| Alternativnummer: | ASB-ARP38135_T100-25UL,ASB-ARP38135_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human JUNB |
| Alternative Synonym: | AP-1 |
| The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation. |
|
|
Rabbit Anti-JUNB Antibody Catalog Number: ARP38135_T100 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
|
|
WB Suggested Anti-JUNB Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Transfected 293T |
|
|
JUNB antibody - N-terminal region (ARP38135_T100) in Transfected 293T using Western Blot |
Produktgarantie und fachkundiger Support
