Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2B
Alternative Synonym:
PDA2, AP-2B, AP2-B, AP-2beta
TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes.