COPS2 Antibody - N-terminal region

Artikelnummer: ASB-ARP38431_T100
Artikelname: COPS2 Antibody - N-terminal region
Artikelnummer: ASB-ARP38431_T100
Hersteller Artikelnummer: ARP38431_T100
Alternativnummer: ASB-ARP38431_T100-25UL,ASB-ARP38431_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
Alternative Synonym: CSN2, SGN2, ALIEN, TRIP15
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 51kDa
NCBI: 9318
UniProt: P61203
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Skin
WB Suggested Antibody Titration: 2.5 ug/ml
Positive Control: 293TCOPS2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells
COPS2 antibody - N-terminal region (ARP38431_T100) in Human HEK293T using Western Blot