The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1
Alternative Synonym:
TREB36, EWS-ATF1, FUS/ATF-1
ATF1 binds the cAMP response element (CRE) (consensus: 5-GTGACGT [AC] [AG]-3), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.