MAF Antibody - N-terminal region
Artikelnummer:
ASB-ARP38607_P050
- Bilder (4)
| Artikelname: | MAF Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP38607_P050 |
| Hersteller Artikelnummer: | ARP38607_P050 |
| Alternativnummer: | ASB-ARP38607_P050-25UL,ASB-ARP38607_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human MAF |
| Alternative Synonym: | CCA4, AYGRP, c-MAF, CTRCT21 |
| MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. |
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ARP38607_P050 |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.3 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation. |
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WB Suggested Anti-MAF Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Hela cell lysate |
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MAF antibody - N-terminal region (ARP38607_P050) in Human HeLa using Western Blot |
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