NFIL3 Antibody - N-terminal region

Artikelnummer: ASB-ARP38613_T100
Artikelname: NFIL3 Antibody - N-terminal region
Artikelnummer: ASB-ARP38613_T100
Hersteller Artikelnummer: ARP38613_T100
Alternativnummer: ASB-ARP38613_T100-25UL,ASB-ARP38613_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Human, Porcine, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFIL3
Alternative Synonym: E4BP4, IL3BP1, NFIL3A, NF-IL3A
NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 51kDa
NCBI: 4783
UniProt: Q14211
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-NFIL3 Antibody
Catalog Number: ARP38613_T100
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-NFIL3 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T
NFIL3 antibody - N-terminal region (ARP38613_T100) in Transfected 293T using Western Blot