PPARD Antibody - N-terminal region

Artikelnummer: ASB-ARP38764_P050
Artikelname: PPARD Antibody - N-terminal region
Artikelnummer: ASB-ARP38764_P050
Hersteller Artikelnummer: ARP38764_P050
Alternativnummer: ASB-ARP38764_P050-25UL,ASB-ARP38764_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast
Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human PPARD
Alternative Synonym: FAAR, NUC1, NUCI, NR1C2, NUCII, PPARB
PPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 49kDa
NCBI: 5467
UniProt: Q03181
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PPARD antibody
Catalog Number: ARP38764_P050
Paraffin Embedded Tissue: Human Placenta cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-PPARD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: 721_B cell lysatePPARD is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
PPARD antibody - N-terminal region (ARP38764_P050) in Human 721_B using Western Blot