TSG101 Antibody - C-terminal region
Artikelnummer:
ASB-ARP38773_T100
- Bilder (4)
| Artikelname: | TSG101 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP38773_T100 |
| Hersteller Artikelnummer: | ARP38773_T100 |
| Alternativnummer: | ASB-ARP38773_T100-25UL,ASB-ARP38773_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human TSG101 |
| Alternative Synonym: | TSG10, VPS23 |
| TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. |
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WB Suggested Anti-TSG101 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysateTSG101 is supported by BioGPS gene expression data to be expressed in HepG2 |
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Host: Rat Target Name: TSG101 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for this antibody is 1-3 ug/mL. Two closely sized isoforms are observed in some samples. |
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TSG101 antibody - C-terminal region (ARP38773_T100) in Rat Brain using Western Blot |
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