IKZF3 Antibody - C-terminal region

Artikelnummer: ASB-ARP39005_P050
Artikelname: IKZF3 Antibody - C-terminal region
Artikelnummer: ASB-ARP39005_P050
Hersteller Artikelnummer: ARP39005_P050
Alternativnummer: ASB-ARP39005_P050-25UL,ASB-ARP39005_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IKZF3
Alternative Synonym: AIO, AIOLOS, ZNFN1A3
IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 58kDa
NCBI: 22806
UniProt: Q9UKT9
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-IKZF3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T
Host: Mouse
Target Name: IKZF3
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml
IKZF3 antibody - C-terminal region (ARP39005_P050) in Transfected 293T using Western Blot