The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT7
Alternative Synonym:
CAF1, CAF-1, Caf1a, hCAF-1
CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
WB Suggested Anti-CNOT7 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysateCNOT7 is supported by BioGPS gene expression data to be expressed in HepG2
CNOT7 antibody - N-terminal region (ARP39026_P050) in Human HepG2 using Western Blot
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