BCL11A Antibody - N-terminal region
Artikelnummer:
ASB-ARP39322_P050
- Bilder (3)
| Artikelname: | BCL11A Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP39322_P050 |
| Hersteller Artikelnummer: | ARP39322_P050 |
| Alternativnummer: | ASB-ARP39322_P050-25UL,ASB-ARP39322_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Human, Mouse, Porcine, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human BCL11A |
| Alternative Synonym: | EVI9, CTIP1, DILOS, ZNF856, HBFQTL5, BCL11A-L, BCL11A-S, BCL11a-M, BCL11A-XL |
| BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. |
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Immunohistochemistry with Human Spleen lysate tissue at an antibody concentration of 5.0ug/ml using anti-BCL11A antibody (ARP39322_P050) |
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WB Suggested Anti-BCL11A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human heart |
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BCL11A antibody - N-terminal region (ARP39322_P050) in Human heart using Western Blot |
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