PRDM12 Antibody - C-terminal region

Artikelnummer: ASB-ARP39504_T100
Artikelname: PRDM12 Antibody - C-terminal region
Artikelnummer: ASB-ARP39504_T100
Hersteller Artikelnummer: ARP39504_T100
Alternativnummer: ASB-ARP39504_T100-25UL,ASB-ARP39504_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Human, Mouse, Porcine, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
Alternative Synonym: PFM9, HSAN8
PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 40 kDa
NCBI: 59335
UniProt: Q9H4Q4
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 2 ug/mL of the antibody was used in this experiment.
WB Suggested Anti-PRDM12 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
PRDM12 antibody - C-terminal region (ARP39504_T100) in Human HepG2 using Western Blot