INSIG1 Antibody - middle region
Artikelnummer:
ASB-ARP40161_P050
- Bilder (2)
| Artikelname: | INSIG1 Antibody - middle region |
| Artikelnummer: | ASB-ARP40161_P050 |
| Hersteller Artikelnummer: | ARP40161_P050 |
| Alternativnummer: | ASB-ARP40161_P050-25UL,ASB-ARP40161_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human INSIG1 |
| Alternative Synonym: | CL6 |
| Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain |
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INSIG1 antibody - middle region (ARP40161_P050) in Human Brain using Western Blot |
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